Description

Fmoc-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs)[1].-4°C (Powder, protect from light)-Applications-Cancer-programmed cell death-Formula-C28H29N3O5-Citation–References-[1]Wayne C Widdison, et al. Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolites in Cancer Cells and Induce High Levels of Bystander Killing. Bioconjug Chem. 2015 Nov 18;26(11):2261-78. -CASNumber-1384263-83-5-MolecularWeight-487.55-Compound Purity-98.86-SMILES-OCC(C=C1)=CC=C1NC([C@H](C)NC([C@H](C)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O-Research_Area-Cancer-Solubility-DMSO : 125 mg/mL (ultrasonic)-Target-ADC Linker-Isoform-Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related