Description

Feglymycin is a HIV replication inhibitor. Feglymycin is also an antibiotic peptide that has antibacterial activity (MIC: 32-64 μg/mL for Staphylococcus aureus)[1].—–C95H97N13O30—-[1]Dettner F, et al. Total synthesis of the antiviral peptide antibiotic feglymycin. Angew Chem Int Ed Engl. 2009;48(10):1856-61.|[2]Vértesy L, et al. Feglymycin, a novel inhibitor of the replication of the human immunodeficiency virus. Fermentation, isolation and structure elucidation. J Antibiot (Tokyo). 1999 Apr;52(4):374-82.–209335-49-9–1900.86—-O=C(N[C@H](C1=CC(O)=CC(O)=C1)C(N[C@@H](C2=CC=C(O)C=C2)C(N[C@H](C3=CC(O)=CC(O)=C3)C(N[C@@H](C(C)C)C(N[C@H](C4=CC(O)=CC(O)=C4)C(N[C@@H](C5=CC=C(O)C=C5)C(N[C@H](C(N[C@H](C(O)=O)CC(O)=O)=O)CC6=CC=CC=C6)=O)=O)=O)=O)=O)=O)[C@H](C7=CC=C(O)C=C7)NC([C@@H](C8=CC(O)=CC(O)=C8)NC([C@H](C(C)C)NC([C@@H](C9=CC(O)=CC(O)=C9)NC([C@@H](C=CC=C(O)C=C)N)=O)=O)=O)=O–Infection–10 mM in DMSO–Bacterial;HIV—-Anti-infection–Peptides