Description

FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO). FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL)-treated cells, PRL regulates CPD mRNA levels in cells[1].—Metabolism-protein/nucleotide metabolism–C16H23N5O5—-[1]Abdelmagid SA, et al. Prolactin and estrogen up-regulate carboxypeptidase-d to promote nitric oxide production and survival of mcf-7 breast cancer cells. Endocrinology. 2008 Oct;149(10):4821-8.–76079-06-6–365.38—-N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](C)NC(/C=C/C1=CC=CO1)=O)=O–Endocrinology–10 mM in DMSO–Endogenous Metabolite—-Metabolic Enzyme/Protease–Peptides