Description

Erlotinib-d6 (hydrochloride) a deuterium labeled Erlotinib Hydrochloride. Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM[1]. Erlotinib-d6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.–20°C, 3 years (Powder)-Applications-Cancer-Kinase/protease-Formula-C22H18D6ClN3O4-Citation–References-[1]Moyer JD, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. 1997 Nov 1;57(21):4838-48.-CASNumber-1189953-78-3-MolecularWeight-435.93-Compound Purity-98.13-SMILES-[2H]C([2H])([2H])OCCOC1=CC2=NC=NC(NC3=CC=CC(C#C)=C3)=C2C=C1OCCOC([2H])([2H])[2H].[H]Cl-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-Autophagy;EGFR-Isoform–Pathway-Autophagy;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK-MCE Product type-Isotope-Labeled Compounds