Description

:Unconjugated;host:Mouse;target_protein:ERAB;modification:Unmodified;clonality:Polyclonal;isotype:IgG;concentration:1ug/ul;subcellular_locations:Cytoplasm;source:KLH conjugated synthetic peptide derived from human ERAB;gene_id:3028;swiss_prot:;applications_with_dilutions:ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200);cross_reactive_species:;predicted_cross_reactive_species:Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Guinea Pig;background:This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer’s disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].;purification:Purified by Protein A.;storage_buffer:0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.;storage_condition:Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.;:;synonyms:HSD17B10; Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase; 17 beta hydroxysteroid dehydrogenase 10; 17 beta hydroxysteroid dehydrogenase type 10; 17b HSD10; 3 hydroxy 2 methylbutyryl CoA dehydrogenase; 3 hydroxyacyl CoA dehydrogenase type 2;