EGTA-1 g
Description
EGTA is a specific calcium ion chelator. EGTA has an apparent calcium dissociation constant (Kd) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca2+ over Mg2+ (Mg2+ Kd 1-10 mM). EGTA significantly inhibits the substrate adherence capacity of inflammatory macrophages[1][2].–20°C, 3 years; 4°C, 2 years (Powder)-Applications–Formula-C14H24N2O10-Citation–References-[1]Harris RA, Hanrahan JW. Effects of EGTA on calcium signaling in airway epithelial cells. Am J Physiol. 1994;267(5 Pt 1):C1426-C1434. doi:10.1152/ajpcell.1994.267.5.C1426|[2]Segura-Egea JJ, Jiménez-Rubio A, Rios-Santos JV, Velasco-Ortega E, Calvo-Gutierrez JR. In vitro inhibitory effect of EGTA on macrophage adhesion: endodontic implications. J Endod. 2003;29(3):211-213.-CASNumber-67-42-5-MolecularWeight-380.35-Compound Purity-98.0-SMILES-O=C(O)CN(CC(O)=O)CCOCCOCCN(CC(O)=O)CC(O)=O-Research_Area-Inflammation/Immunology-Solubility-DMSO : 1 mg/mL (ultrasonic)|H2O : 5 mg/mL (ultrasonic;warming;adjust pH to 9 with NaOH;heat to 60°C)-Target-Biochemical Assay Reagents-Isoform–Pathway-Others-MCE Product type-Biochemical Assay Reagents