Description

DMAC-PDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].–Applications-Cancer-programmed cell death-Formula-C12H16N2O3S2-Citation–References-[1]Wayne Charles Widdison, et al. Cross-linkers with high reactivity and solubility and their use in the preparation of conjugates for targeted delivery of small molecule drugs. WO2004016801A2-CASNumber-663599-04-0-MolecularWeight-300.40-Compound Purity–SMILES-O=C(O)CCCSSC1=NC=C(C(N(C)C)=O)C=C1-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker-Isoform-Cleavable Linker;Disulfide Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related