Disomotide
Description
Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma[1][2].—–C47H74N10O14S—-[1]Yang S, et al. Antimelanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity. J Immunol. 2002 Jul 1;169(1):531-9.|[2]Ahmadzadeh M, et al. IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells. J Immunother. 2007 Apr;30(3):294-302.–181477-43-0–1035.21—-O=C(N(CCC1)[C@@H]1C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(O)=O)C(C)C)=O)=O)CC2=CC=CC=C2)=O)[C@H](C(C)C)NC([C@H](CCC(N)=O)NC([C@H](CC(O)=O)NC([C@H](CCSC)NC([C@@H](N)[C@@H](C)CC)=O)=O)=O)=O–Cancer–10 mM in DMSO–Others—-Others–Peptides