Description

Dibromomaleimide-C5-COOH (DBM-C5-COOH) is a bifunctional dibromomaleimide (DBM) linker. Dibromomaleimide-C5-COOH can be used to connect MMAF and to synthesize ADC[1].-4°C (Powder, stored under nitrogen)-Applications-Cancer-programmed cell death-Formula-C10H11Br2NO4-Citation–References-[1]Behrens CR, et al. Antibody-Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs. Mol Pharm. 2015 Nov 2;12(11):3986-98. -CASNumber-1443214-97-8-MolecularWeight-369.01-Compound Purity-99.30-SMILES-O=C(CCCCCN1C(C(Br)=C(C1=O)Br)=O)O-Research_Area-Others-Solubility-DMSO : ≥ 100 mg/mL-Target-ADC Linker-Isoform–Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related