Description

DiAzKs (H-L-Photo-lysine) is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs acts as a UV light-activated photo-crosslinking probe[1][2][3].-4°C (Powder, protect from light)-Applications–Formula-C11H20N4O4-Citation–References-[1]Ai HW, et al. Probing protein-protein interactions with a genetically encoded photo-crosslinking amino acid. Chembiochem. 2011 Aug 16;12(12):1854-7.|[2]Chatterjee A, et al. Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11803-8.|[3]Yang T, et al. Photo-lysine captures proteins that bind lysine post-translational modifications. Nat Chem Biol. 2016 Feb;12(2):70-2.-CASNumber-1253643-88-7-MolecularWeight-272.30-Compound Purity-98.0-SMILES-N[C@@H](CCCCNC(OCCC1(C)N=N1)=O)C(O)=O-Research_Area-Others-Solubility-DMSO : 2 mg/mL (ultrasonic)|H2O : 5 mg/mL (ultrasonic)-Target-Fluorescent Dye-Isoform–Pathway-Others-MCE Product type-Dye Reagents