Description

Desmethyl Vc-seco-DUBA consists a cleavable ADC linker (Desmethyl Vc-seco) and a DNA alkylating agent (DUBA). Desmethyl Vc-seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs)[1].–Applications-Cancer-programmed cell death-Formula-C64H73ClN12O17-Citation–References-[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.-CASNumber–MolecularWeight-1317.79-Compound Purity–SMILES-O=C(N(CCN(CCOCCO)C(OC1=CC2=C(C3=CC=CC=C31)[C@H](CCl)CN2C(C4=CN5C=C(NC(C6=CC=C(O)C=C6)=O)C=CC5=N4)=O)=O)C)OCC7=CC=C(C=C7)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCCOCCN8C(C=CC8=O)=O)=O)=O)=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-Drug-Linker Conjugates for ADC-Isoform-Duocarmycins-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related