Description

Defensin HNP-1 human is a Human neutrophil peptides (HNPs), involved in endothelial cell dysfunction at the time of early atherosclerotic development. Defensin HNP-1 human exhibits broad antimicrobial and anti-leishmanial activities[1][2].—Metabolism-protein/nucleotide metabolism–C150H222N44O38S6—-[1]Dabirian S, et, al. Human neutrophil peptide-1 (HNP-1): a new anti-leishmanial drug candidate. PLoS Negl Trop Dis. 2013 Oct 17;7(10):e2491.|[2]Higazi M, et, al. Opposing effects of HNP1 (α-defensin-1) on plasma cholesterol and atherogenesis. PLoS One. 2020 Apr 17;15(4):e0231582.–148093-65-6–3442.03—-O=C([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@](NC([C@@]1([H])NC([C@](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@](NC([C@]2([H])CSSC[C@](C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N[C@](CSSC1)([H])C(N[C@H](C(N[C@@](C(N3[C@](CCC3)([H])C(N[C@H](C(N2)=O)C)=O)=O)([H])[C@@H](C)CC)=O)CCCNC(N)=N)=O)=O)CC4=CC=C(C=C4)O)=O)NC([C@@H](N)C)=O)C(O)=O)=O)([H])NC([C@@H](NC([C@@H](NC5=O)C)=O)CC6=CC=CC=C6)=O)=O)([H])[C@@H](C)CC)=O)C)=O)=O)CCC(O)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CC7=CC=C(C=C7)O)=O)=O)([H])[C@H](O)C)=O)=O)([H])[C@@H](C)CC)=O)CC8=CC=C(C=C8)O)=O)CCC(N)=O)=O)=O)CCCNC(N)=N)=O)CC(C)C)N[C@H]5CC9=CNC=CC=CC=C9–Infection; Cardiovascular Disease–H2O–Bacterial;Parasite–Leishmania–Anti-infection–Peptides