Description

DBCO-PEG4-alkyne is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.–Applications-Cancer-programmed cell death-Formula-C30H34N2O6-Citation–References-[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.-CASNumber-2741418-16-4-MolecularWeight-518.60-Compound Purity–SMILES-O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCOCCOCCOCCOCC#C)=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker-Isoform-Non-cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related