DBCO-amine-5 mg

Description

DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.–20°C (Powder, protect from light)-Applications-Cancer-programmed cell death-Formula-C18H16N2O-Citation–References-[1]Ermira Pazolli, et al. Splicing modulator antibody-drug conjugates and methods of use. WO2019232449A1.-CASNumber-1255942-06-3-MolecularWeight-276.33-Compound Purity-99.77-SMILES-O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCN-Research_Area-Cancer-Solubility-DMSO : 100 mg/mL (ultrasonic)-Target-ADC Linker-Isoform-Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related