Description

DALDA TFA is a potent and highly selective μ-opioid receptor agonist with a Ki of 1.69 nM. DALDA TFA shows antinociceptive and respiratory effects[1].—–C30H45N9O5.xC2HF3O2—-[1]Shimoyama M, et al. Antinociceptive and respiratory effects of intrathecal H-Tyr-D-Arg-Phe-Lys-NH2 (DALDA) and [Dmt1] DALDA. Journal of Pharmacology and Experimental Therapeutics, 2001, 297(1): 364-371.|[2]Meyer ME, et al. DALDA (H-Tyr-D-Arg-Phe-Lys-NH2), a potent mu-opioid peptide agonist, affects various patterns of locomotor activities. Pharmacol Biochem Behav. 1995 May;51(1):149-51.—-611.74 (free base)—-OC(C=C1)=CC=C1C[C@H](N)C(N[C@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CC2=CC=CC=C2)=O)=O.OC(C(F)(F)F)=O.[x]–Neurological Disease–10 mM in DMSO–Opioid Receptor—-GPCR/G Protein;Neuronal Signaling–Peptides