[D-Trp7,9,10]-Substance P (TFA)-Get quote

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[D-Trp7,9,10]-Substance P TFA is a substance P analogue. Substance P stimulates substance P receptors but also inhibits ion conductance through nicotinic acetylcholine receptors[1].—Neuroscience-Neuromodulation–C79H105N21O13S.xC2HF3O2—-[1]Eardley D, et al. Both substance P agonists and antagonists inhibit ion conductance through nicotinic acetylcholine receptors on PC12 cells. Eur J Pharmacol. 1985;114(1):101-104.|[2]Mukai H, et al. G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J Biol Chem. 1992;267(23):16237-16243.—-1588.88 (free base)—-OC(C(F)(F)F)=O.CSCC[C@@H](C(N)=O)NC([C@@H](CC1=CNC2=CC=CC=C12)NC([C@H](NC([C@H](CC3=CC=CC=C3)NC([C@H](NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H]4N(CCC4)C([C@H](CCCCN)NC([C@H]5N(CCC5)C([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O)CC8=CNC9=CC=CC=C89)=O)=O–Endocrinology–10 mM in DMSO–mAChR—-GPCR/G Protein;Neuronal Signaling–Peptides