(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide-Get quote

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(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide (Compound 4) is a somatostatin analog with Kds of 0.61, 11.05, 23.5, 1200 and >1000 nM for SSTR5, SSTR3, SSTR2, SSTR1 and SSTR4, respectively[1].—Neuroscience-Neuromodulation–C50H67N11O10S2—-[1]Nikiforovich GV, et al. Molecular modeling suggests conformational scaffolds specifically targeting five subtypes of somatostatin receptors. Chem Biol Drug Des. 2007 Mar;69(3):163-9.–340821-13-8–1046.26—-CN(C([C@@H](NC([C@H](CSSC[C@H](NC([C@](NC([C@@H](NC1=O)CCCCN)=O)([H])[C@H](O)C)=O)C(N[C@H](C(N)=O)[C@H](O)C)=O)NC([C@H](N)CC2=CC=CC=C2)=O)=O)CC3=CC=CC=C3)=O)[C@@H]1CC4=CNC5=CC=CC=C45–Neurological Disease–H2O–Somatostatin Receptor—-GPCR/G Protein;Neuronal Signaling–Peptides