Description

D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase. D-Ala-D-Ala is a bacterial endogenous metabolite[1][2].–20°C, 3 years; 4°C, 2 years (Powder)–Metabolism-protein/nucleotide metabolism–C6H12N2O3—-[1]Kitamura Y, et al. Structure of D-alanine-D-alanine ligase from Thermus thermophilus HB8: cumulative conformational change and enzyme-ligand interactions. Acta Crystallogr D Biol Crystallogr. 2009 Oct;65(Pt 10):1098-106.|[2]Tytgat I, et al. DD-ligases as a potential target for antibiotics: past, present and future. Curr Med Chem. 2009;16(20):2566-80.–923-16-0–160.17–97.0–C[C@H](C(O)=O)NC([C@@H](C)N)=O–Others–DMSO : 2 mg/mL (ultrasonic;adjust pH to 5 with HCl)|H2O : 100 mg/mL (ultrasonic)–Endogenous Metabolite–Microbial Metabolite–Metabolic Enzyme/Protease–Peptides