Description

Cyclosomatostatin is a potent somatostatin (SST) receptor antagonist. Cyclosomatostatin can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size and sphere-formation in colorectal cancer (CRC) cells[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)–Cancer-programmed cell death–C44H57N7O6—-[1]Shirin R Modarai, et al. Somatostatin signaling via SSTR1 contributes to the quiescence of colon cancer stem cells. BMC Cancer. 2016 Dec 7;16(1):941.–84211-54-1–779.97–99.52–O=C(N[C@@](C(N[C@@]1([H])[C@@H](C)OCC2=CC=CC=C2)=O)([H])CCCCN)[C@H](NC([C@@H](NC(CCCCCCNC1=O)=O)CC3=CC=CC=C3)=O)CC4=CNC5=C4C=CC=C5–Cancer–H2O : 10 mg/mL (ultrasonic)–Somatostatin Receptor–SSTR1–GPCR/G Protein;Neuronal Signaling–Peptides