Description

CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer[1].–20°C, 3 years; 4°C, 2 years (Powder)–Cancer-programmed cell death–C25H23Cl2N5O3—-[1]Hess D,et al. Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells. PLoS One. 2010; 5(6):e11394.–1018674-83-3–512.39–99.88–CC(NCCN1C2=NC(NCC3=CC=C(C(Cl)=C3)Cl)=CC=C2N=C(C1=O)C4=CC=C(C=C4)OC)=O–Cancer–DMSO : 25 mg/mL (ultrasonic)–Apoptosis;Stearoyl-CoA Desaturase (SCD)—-Apoptosis;Metabolic Enzyme/Protease–Peptides