Description

:HRP;host:Rabbit;target_protein:CREB-1 Ser133;modification:Phosphorylation;clonality:Polyclonal;isotype:IgG;concentration:1ug/ul;subcellular_locations:Nucleus;source:KLH conjugated synthetic phosphopeptide derived from human CREB-1 around the phosphorylation site of Ser133 [RP(p-S)YR];gene_id:1385;swiss_prot:P16220;applications_with_dilutions:WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500);cross_reactive_species:Human, Mouse, Rat, Pig;predicted_cross_reactive_species:Dog, Cow, Sheep, Chicken;background:Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.;purification:Purified by Protein A.;storage_buffer:Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.;storage_condition:Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.;:N/A;synonyms:CREB; Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1; CREB1