[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide-5 mg

Description

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist with an IC50 of 0.24 nM for binding to the hY5 receptor. [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide induces a high amount of food intake[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)–Neuroscience-Neuromodulation–C183H281N57O54S2—-[1]C Cabrele , et al. The first selective agonist for the neuropeptide YY₅ receptor increases food intake in rats. J Biol Chem. 2000 Nov 17;275(46):36043-8.–313988-89-5–4207.66–99.65–O=C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N2[C@@H](CCC2)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC3=CC=C(C=C3)O)C(N4[C@@H](CCC4)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(N5[C@@H](CCC5)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCSC)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC6=CC=C(C=C6)O)C(N[C@@H](CC7=CC=C(C=C7)O)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC8=CC=C(C=C8)O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](CCSC)C(N[C@@H](C)C(NC(C)(C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC9=CC=C(C=C9)O)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN–Neurological Disease–H2O : 100 mg/mL (ultrasonic)–Neuropeptide Y Receptor–NPY Y1 receptor;NPY Y2 receptor;NPY Y4 receptor;NPY Y5 receptor–GPCR/G Protein;Neuronal Signaling–Peptides