Description

CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons[1].—Neuroscience-Neuromodulation–C19H32O2—-[1]Urwyler S, et al. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol Pharmacol. 2001; 60(5):963-71.–57717-80-3–292.46—-OCC(C)(C)CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1–Neurological Disease–10 mM in DMSO–GABA Receptor—-Membrane Transporter/Ion Channel;Neuronal Signaling–Peptides