Description

Cefilavancin (TD-1792) is a potent multivalent glycopeptide-cephalosporin heterodimer antibiotic with effective activity against Gram-positive bacteria. Cefilavancin has been used to research skin infections[1][2][3].—COVID-19-immunoregulation–C87H95Cl3N16O28S2—-[1]Blais J, et al. Antistaphylococcal activity of TD-1792, a multivalent glycopeptide-cephalosporin antibiotic. Antimicrob Agents Chemother. 2012 Mar;56(3):1584-7.|[2]Stryjewski ME, et al. TD-1792 versus vancomycin for treatment of complicated skin and skin structure infections. Antimicrob Agents Chemother. 2012 Nov;56(11):5476-83.|[3]Hegde SS, et al. Pharmacodynamics of TD-1792, a novel glycopeptide-cephalosporin heterodimer antibiotic used against Gram-positive bacteria, in a neutropenic murine thigh model. Antimicrob Agents Chemother. 2012 Mar;56(3):1578-83.–1393900-12-3–1983.26—-[O-]C(C1=C(C[N+]2=CC=CC=C2)CS[C@@]([C@@H]3NC(/C(C4=C(SC(N)=N4)Cl)=NOCCCNC([C@@H]5C6=CC(O)=CC(O)=C6C7=CC([C@]8([H])C(N[C@]([C@@H](C9=CC=C(OC=CC([C@](NC([C@@H](NC([C@@H]([C@@H](C=CC=C(O)C(Cl)=C)O)NC([C@H](NC)CC(C)C)=O)=O)CC(N)=O)=O)([H])C(N8)=O)=CC=CO[C@H][C@@H]([C@H]([C@@H]([C@H](O)CO)O)O)O[C@H]C[C@](N)([C@@H]([C@@H](O)C)O)C)C(Cl)=C9)O)([H])C(N5)=O)=O)=CC=C7O)=O)=O)([H])N1C3=O)=O–Infection–10 mM in DMSO–Antibiotic;Bacterial–Glycopeptide–Anti-infection–Peptides