Description

:AbBy Fluor® 488;host:Rabbit;target_protein:Caspase-13 + 4;modification:Unmodified;clonality:Polyclonal;isotype:IgG;concentration:1ug/ul;subcellular_locations:Cytoplasm;source:KLH conjugated synthetic peptide derived from bovine Caspase-13;gene_id:;swiss_prot:;applications_with_dilutions:WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200);cross_reactive_species:;predicted_cross_reactive_species:Cow;background:Caspase-13 (also designated Evolutionarily related interleukin-1beta converting enzyme ; ERICE) involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. [subunit] Heterodimer of a small and a large subunit. The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8. Mainly expressed in peripheral blood lymphocytes, spleen and placenta. Belongs to peptidase family C14.;purification:Purified by Protein A.;storage_buffer:Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.;storage_condition:Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.;:499nm/519nm;synonyms:CASP-13; CASP4; Caspase 13 subunit 1; Caspase 13 subunit 2; Caspase 4; Caspase 4 subunit 1; Caspase 4, apoptosis related cysteine; CASPD_BOVIN; Caspase-13; Evolutionary related interleukin-1-beta-converting enzyme; ERICE.