C-11-Get quote

Description

C-11 is a tubulin inhibitor and acts as an ADC cytotoxin, displays cytotoxicity for carcinoma cell lines[1].–Applications-Cancer-programmed cell death-Formula-C38H58N6O7S-Citation–References-[1]Leverett CA, et al. Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads. ACS Med Chem Lett. 2016 Aug 26;7(11):999-1004.-CASNumber-2007965-97-9-MolecularWeight-742.97-Compound Purity–SMILES-O=C(N(C)[C@@H](C(C)C)C[C@@H](OC(C)=O)C1=NC(C(N[C@@H](CC2=CC=C(N)C=C2)C[C@H](C)C(O)=O)=O)=CS1)[C@H]([C@@H](C)CC)NC([C@@]3(C)CCCN3C)=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Cytotoxin;Microtubule/Tubulin-Isoform-Traditional Cytotoxic Agents-Pathway-Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton-MCE Product type-ADC Related