BWX 46-Get quote

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BWX 46 (((Cys31, Nva 34)-Neuropeptide Y (27-36))2) is a selective Y5 receptor agonist with an IC50 value of 0.85 nM. BWX 46 can inhibit the synthesis of cAMP in Y5 cells[1].—–C116H186N36O28S2—-[1]Balasubramaniam A, et al. Bis(31/31′)[[Cys(31), Nva(34)]NPY(27-36)-NH(2)]: a neuropeptide Y (NPY) Y(5) receptor selective agonist with a latent stimulatory effect on food intake in rats. Peptides. 2002;23(8):1485-1490.–172997-92-1–2597.07—-OC(C=C1)=CC=C1C[C@H](N)C(N[C@]([C@@H](C)CC)([H])C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CSSC[C@@H](C(N[C@]([C@H](O)C)([H])C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC2=CC=C(O)C=C2)=O)=O)=O)=O)=O)NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@@]([C@@H](C)CC)([H])NC([C@@H](N)CC3=CC=C(O)C=C3)=O)=O)=O)=O)C(N[C@]([C@H](O)C)([H])C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC4=CC=C(O)C=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O–Neurological Disease–10 mM in DMSO–Neuropeptide Y Receptor–NPY Y1 receptor;NPY Y2 receptor;NPY Y4 receptor;NPY Y5 receptor–GPCR/G Protein;Neuronal Signaling–Peptides