Description

conjugation-Unconjugated-source-Recombinant mouse EAAT2 protein, N-GST&C-His protein is expressed in E.coli with N-GST&C-His. It contains the amino acid sequence of 460-572/572.-gene_id-20511-swiss_prot-P43006-applications-ELISA-species-Others-background-This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]-storage_buffer-0.01M TBS(pH7.4)-storage_condition-The product should be stored at -70°C or -20°C.-expression_system-E.coli-tag-N-GST&C-His-purity-> 95% as determined by SDS- PAGE-endotoxin-Not Tested