Description

conjugation-Unconjugated-source-Recombinant human NLRP3 protein, C-His protein is expressed in E.coli with C-His. It contains the amino acid sequence of 4-223/1036.-gene_id-114548-swiss_prot-Q96P20-applications-ELISA-species-Others-background-May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm.-storage_buffer-0.01M TBS(pH7.4)-storage_condition-The product should be stored at -70°C or -20°C.-expression_system-E.coli-tag-C-His-purity-> 95% as determined by SDS- PAGE-endotoxin-Not Tested