Description

conjugation-Unconjugated-source-Recombinant human CD3 epsilon protein, His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 23-126/207.-gene_id-12501-swiss_prot-P07766-applications-ELISA-species-Others-background-The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].-storage_buffer-0.01M TBS(pH7.4)-storage_condition-The product should be stored at -70°C or -20°C.-expression_system-E.coli-tag-His-purity-> 95% as determined by SDS- PAGE-endotoxin-Not Tested