Description

Bromoacetamido-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromoacetamido-PEG4-acid is also a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].–20°C, 3 years; 4°C, 2 years (Powder)-Applications-Cancer-programmed cell death-Formula-C13H24BrNO7-Citation–References-[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.|[2]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.-CASNumber-1807518-67-7-MolecularWeight-386.24-Compound Purity-95.0-SMILES-O=C(O)CCOCCOCCOCCOCCNC(CBr)=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker;PROTAC Linkers-Isoform-Cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related