Description

Box5 is a potent Wnt5a antagonist. Box5 inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca2+ release. Box5 inhibits cell migration. Box5 has the potential for the research of melanoma[1].—Cancer-programmed cell death–C30H50N6O13S2—-[1]Jenei V, et al. A t-butyloxycarbonyl-modified Wnt5a-derived hexapeptide functions as a potent antagonist of Wnt5a-dependent melanoma cell invasion. Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19473-8.–1206604-29-6–766.88—-CC(C)C[C@@H](C(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CS)NC(CNC([C@H](CC(O)=O)NC([C@H](CCSC)NC(OC(C)(C)C)=O)=O)=O)=O)=O)=O–Cancer–10 mM in DMSO–Wnt—-Stem Cell/Wnt–Peptides