Boc-NH-PEG4-CH2CH2COOH-100 mg

100 mg

SKU: HY-W040132-100 mg Category: Tags: ,

Description

Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1]. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[2].–20°C, 3 years; 4°C, 2 years (Powder)-Applications-Cancer-programmed cell death-Formula-C16H31NO8-Citation–References-[1]Nathanael Gray, et al. Bifunctional compounds for her3 degradation and methods of use. WO2018114798A1.|[2]Hans-Georg Lerchen, et al. Prodrugs of cytotoxic active agents having enzymatically cleavable groups. WO2018114798A1.-CASNumber-756525-91-4-MolecularWeight-365.42-Compound Purity-99.85-SMILES-CC(C)(OC(NCCOCCOCCOCCOCCC(O)=O)=O)C-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker;PROTAC Linkers-Isoform-Alkyl/ether Linkers;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related

Brand

MEDCHEM EXPRESS

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