Description

Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine (HY-18341). L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4)[1].–Applications-Metabolism-protein/nucleotide metabolism-Formula-C25H25I4N3O6S-Citation–References-[1]Arici M, et al. Association between genetic polymorphism and levothyroxine bioavailability in hypothyroid patients. Endocr J. 2018 Mar 28;65(3):317-323.|[2]Corriveau S, et al. Levothyroxine treatment generates an abnormal uterine contractility patterns in an in vitro animalmodel. J Clin Transl Endocrinol. 2015 Sep 9;2(4):144-149.-CASNumber-149734-00-9-MolecularWeight-1003.17-Compound Purity–SMILES-IC(C=C1C[C@@H](C(O)=O)NC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=C(C(I)=C1)OC4=CC(I)=C(C(I)=C4)O-Research_Area-Endocrinology-Solubility-10 mM in DMSO-Target-Endogenous Metabolite;Thyroid Hormone Receptor-Isoform–Pathway-Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor-MCE Product type-Dye Reagents