Description

:AbBy Fluor® 750;host:Rabbit;target_protein:Bcl-2;modification:Unmodified;clonality:Polyclonal;isotype:IgG;concentration:1ug/ul;subcellular_locations:Cytoplasm, Nucleus, Cell membrane;source:KLH conjugated synthetic peptide derived from rat Bcl-2 ;gene_id:24224;swiss_prot:P49950;applications_with_dilutions:WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200);cross_reactive_species:Human, Mouse, Rat, Bovine, Chicken, Rabbit, Bacteria;predicted_cross_reactive_species:Dog, Cow, Pig, Horse;background:Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).;purification:Purified by Protein A.;storage_buffer:Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.;storage_condition:Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.;:749nm/775nm;synonyms:Bcl-2; Apoptosis regulator Bcl-2; Bcl2