Description

Batifiban, a cyclic peptide, is a platelet glycoprotein GPⅡb/Ⅲa antagonist, and inhibits platelet aggregation. Batifiban blocks circulating vitronectin binding to integrin ανβ3, Batifiban can be used for research of acute coronary syndromes[1].—–C34H47N11O9S2—-[1]Chen H, et al. Safety, pharmacokinetic and pharmacodynamic studies of batifiban injection following single- and multiple-dose administration to healthy Chinese subjects. J Huazhong Univ Sci Technolog Med Sci. 2009 Feb;29(1):12-8.–710312-77-9–817.94—-O=C(N1[C@@](C(N[C@@H](CSSCCC2=O)C(N)=O)=O)([H])CCC1)[C@@H](NC([C@@H](NC(CNC([C@@H](N2)CCCNC(N)=N)=O)=O)CC(O)=O)=O)CC3=CNC4=CC=CC=C34–Cardiovascular Disease–10 mM in DMSO–Integrin—-Cytoskeleton–Peptides