Description

AR-M1896 is a GalR2 selective agonist with a binding IC50 of 1.76 nM for rat GalR2. AR-M1896 can be used for the research of acute myocardial infarction and neuropathic pain[1][2].—–C54H81N13O14—-[1]Serebryakova L, et al. Galanin and its N-terminal fragments reduce acute myocardial infarction in rats. Peptides. 2019 Jan;111:127-131.|[2]Liu HX, et al. Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective actions via GalR1 and GalR2 receptors. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9960-4.–367518-31-8–1136.30—-OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CC(C)C)=O)=O)NC(CNC([C@H](C)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@@]([C@H](O)C)([H])NC([C@@H](N)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O)=O)=O)=O–Neurological Disease–10 mM in DMSO–Neuropeptide Y Receptor—-GPCR/G Protein;Neuronal Signaling–Peptides