Description

APTSTAT3-9R, a specific STAT3-binding peptide, inhibits STAT3 activation and downstream signaling by specifically blocking STAT3 phosphorylation. APTSTAT3-9R exerts antiproliferative effects and antitumor activity[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)–Cancer-Kinase/protease–C223H330N80O51—-[1]Daejin Kim, et al. A Specific STAT3-binding Peptide Exerts Antiproliferative Effects and Antitumor Activity by Inhibiting STAT3 Phosphorylation and Signaling. Cancer Res. 2014 Apr 15;74(8):2144-51.—-4947.51–99.55–O=C(NCC(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N4[C@@H](CCC4)C(NCC(N[C@@H](CO)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC7=CNC8=CC=CC=C78)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CC9=CNC=CC=CC=C9)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC=CNC=CC=CC=C)C(N[C@@H](CCCCN)C(NCC(N[C@@H](C)C(N[C@@H](CC=CC=C(C=C)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC=CC=CC=C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(NCC(NCC(NCC(NCC(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC=CNC=N)N–Cancer–10 mM in DMSO–STAT–STAT3–JAK/STAT Signaling;Stem Cell/Wnt–Peptides