Description

Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, is a weak sst2/sst5 receptor partial agonist with IC50 values of 0.26 nM and 6.92 nM, respectively. Angiopeptin TFA is a potent inhibitor of growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin TFA inhibits adenylate cyclase or stimulates extracellular acidification. Angiopeptin TFA has the potential for coronary atherosclerosis research[1][2].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)–Neuroscience-Neuromodulation–C58H73F6N11O14S2—-[1]Lundergan CF, et al. Peptide inhibition of myointimal proliferation by angiopeptin, a somatostatin analogue. J Am Coll Cardiol. 1991;17(6 Suppl B):132B-136B.|[2]Alderton F, et al. Somatostatin receptor-mediated arachidonic acid mobilization: evidence for partial agonism of synthetic peptides. Br J Pharmacol. 2001;132(3):760-766.–2478421-60-0–1326.39–99.71–C[C@@H](O)[C@@H](C(N)=O)NC([C@H](CS)NC([C@H](C(C)C)NC([C@H](CCCCN)NC([C@@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC3=CC=C(O)C=C3)NC([C@H](CS)NC([C@@H](CC4=CC=C5C=CC=CC5=C4)N)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O–Cardiovascular Disease–H2O : 10 mg/mL (ultrasonic)–Adenylate Cyclase;Somatostatin Receptor–SSTR2;SSTR5–GPCR/G Protein;Neuronal Signaling–Peptides