Description

AMPR-22 is an antimicrobial peptide. AMPR-22 can bind to the bacterial membrane and induces membrane permeabilization. AMPR-22 is effective against murine model of sepsis induced by MDR strains[1]—–C98H168N28O22S3—-[1]Kim H, et al. Identification of Bacterial Membrane Selectivity of Romo1-Derived Antimicrobial Peptide AMPR-22 via Molecular Dynamics. Int J Mol Sci. 2022 Jul 3;23(13):7404.–2569135-98-2–2186.75—-N=C(N)NCCC[C@@H](C(O)=O)NC([C@H]([C@@H](C)CC)NC(CNC(CNC([C@H]([C@@H](C)CC)NC([C@H](C)NC([C@H](CCSC)NC([C@@H](NC([C@H]([C@H](O)C)NC(CNC([C@@H](NC([C@H](CCCCN)NC(CNC(CNC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCSC)NC([C@H](CCSC)NC([C@H](CCCCN)NC([C@@H](N)CCCCN)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)=O–Infection–10 mM in DMSO–Bacterial—-Anti-infection–Peptides