Amino-PEG4-CH2COOH-250 mg
Description
Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].-4°C (Powder, protect from light)-Applications-Cancer-programmed cell death-Formula-C10H21NO6-Citation–References-[1]Nan JI, et al. Mertk degraders and uses thereof. WO2020010210A1.|[2]Maggie Lu, et al. Linker-drug and antibody-drug conjugate (adc) employing the same. EP3335734A1.-CASNumber-195071-49-9-MolecularWeight-251.28-Compound Purity-98.0-SMILES-O=C(O)COCCOCCOCCOCCN-Research_Area-Cancer-Solubility-DMSO : 100 mg/mL (ultrasonic)-Target-ADC Linker;PROTAC Linkers-Isoform-Non-cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related