Amino-PEG4-alcohol-100 mg

Description

Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].-4°C (Powder, protect from light)-Applications-Cancer-programmed cell death-Formula-C8H19NO4-Citation–References-[1]Nello Mainolfi, et al. Protein degraders and uses thereof. WO2019060742A1.|[2]Miller MA, et al. Modular Nanoparticulate Prodrug Design Enables Efficient Treatment of Solid Tumors Using Bioorthogonal Activation. ACS Nano. 2018 Dec 26;12(12):12814-12826.-CASNumber-86770-74-3-MolecularWeight-193.24-Compound Purity-99.73-SMILES-NCCOCCOCCOCCO-Research_Area-Cancer-Solubility-DMSO : ≥ 100 mg/mL|H2O : 100 mg/mL (ultrasonic)-Target-ADC Linker;PROTAC Linkers-Isoform-Non-cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related