Description

alpha-1,3-Galactosyltransferase (a1,3GalT) (GGTA1) catalyzes the generation of the α-gal glycan via the transfer of a galactose (Gal) in α1-3 linkage, from a uridyl-diphosphate (UDP) donor onto the N-acetyllactosamine (Galβ1,4GlcNAc-R) of glycoproteins. alpha-1,3-Galactosyltransferase (a1,3GalT) is responsible for the synthesis of the α-galactose (α-Gal) epitope found in most mammalian species[1].–Applications-Metabolism-protein/nucleotide metabolism-Formula-N/A-Citation–References-[1]Sumnima Singh, et al. Loss of α-gal during primate evolution enhanced antibody-effector function and resistance to bacterial sepsis. Cell Host Microbe. 2021 Mar 10;29(3):347-361.e12.|[2]Anne-Laure Turcot-Dubois, et al. Long-term evolution of the CAZY glycosyltransferase 6 (ABO) gene family from fishes to mammals–a birth-and-death evolution model. Glycobiology. 2007 May;17(5):516-28.-CASNumber-128449-51-4-MolecularWeight-N/A-Compound Purity–SMILES-[alpha-1,3-Galactosyltransferase(a1,3GalT)]-Research_Area-Metabolic Disease-Solubility-10 mM in DMSO-Target-Endogenous Metabolite-Isoform-Human Endogenous Metabolite-Pathway-Metabolic Enzyme/Protease-MCE Product type-Enzyme