Description

Allotetrahydrocortisol-d5 is the deuterium labeled Allotetrahydrocortisol. Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a metabolite of Cortisol. Cortisol is the main glucocorticoid in human. It is produced in adrenal cortex and plays a crucial role in many physiological processes[1][2].–Applications–Formula-C21H29D5O5-Citation–References-[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]BUSH IE, et al. The excretion of allo tetrahydrocortisol in human urine. Biochem J. 1957 Dec;67(4):689-700.|[3]Kosicka K, et al. Detailed analysis of cortisol, cortisone and their tetrahydro- and allo-tetrahydrometabolites in human urine by LC-MS/MS. J Pharm Biomed Anal. 2017 Jun 5;140:174-181.-CASNumber-2687961-06-2-MolecularWeight-371.52-Compound Purity–SMILES-C[C@@]12[C@](C(CO)=O)(O)CC[C@@]1([H])[C@]3([H])CC[C@@]4([H])C([2H])([2H])[C@@](O)([2H])C([2H])([2H])C[C@]4(C)[C@@]3([H])[C@@H](O)C2-Research_Area-Others-Solubility-10 mM in DMSO-Target-Endogenous Metabolite;Isotope-Labeled Compounds-Isoform–Pathway-Metabolic Enzyme/Protease;Others-MCE Product type-Isotope-Labeled Compounds