Description

(Ala13)-Apelin-13 TFA is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 TFA inhibits gastric motility through vagal cholinergic pathway[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)–Neuroscience-Neuromodulation–C63H107N23O16S.xC2HF3O2—-[1]O’Harte FPM,et al. Acylated apelin-13 amide analogues exhibit enzyme resistance and prolonged insulin releasing, glucose lowering and anorexic properties. Biochem Pharmacol. 2017 Dec 15;146:165-173.|[2]Bülbül M, et al. Apelin-13 inhibits gastric motility through vagal cholinergic pathway in rats. Am J Physiol Gastrointest Liver Physiol. 2018 Feb 1;314(2):G201-G210.—-1474.73 (free acid)–99.25–NC(CC[C@H](N)C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCCCN)C(NCC(N2[C@@H](CCC2)C(N[C@@H](CCSC)C(N3[C@@H](CCC3)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)CC4=CN=CN4)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O.[x]–Cardiovascular Disease–10 mM in DMSO–Apelin Receptor (APJ)—-GPCR/G Protein–Peptides