Description

Ala-Ala-Asn-PAB is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs)[1].–Applications-Cancer-programmed cell death-Formula-C17H25N5O5-Citation–References-[1]Cheng X, et al. MORAb-202, an Antibody-Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity. Mol Cancer Ther. 2018 Dec;17(12):2665-2675.-CASNumber-2149584-00-7-MolecularWeight-379.41-Compound Purity–SMILES-OCC1=CC=C(NC([C@H](CC(N)=O)NC([C@H](C)NC([C@@H](N)C)=O)=O)=O)C=C1-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker-Isoform-Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related