Description

Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection[1][2].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)–COVID-19-immunoregulation–C62H84N12O17—-[1]Liu J, et al. Apoptosis of human prostate cancer cells induced by marine actinomycin X2 through the mTOR pathway compounded by MiRNA144. Anticancer Drugs. 2016 Mar;27(3):156-63.|[2]Zhiyu Chen, et al. Anti-MRSA Activity of Actinomycin X 2 and Collismycin A Produced by Streptomyces globisporusWA5-2-37 From the Intestinal Tract of American Cockroach ( Periplaneta americana). Front Microbiol. 2020 Apr 7;11:555.–18865-48-0–1269.40–98.0–O=C(N[C@H](C(N[C@H](C(C)C)C(N([C@@]([H])(C1)C2=O)CC1=O)=O)=O)[C@@H](C)OC([C@H](C(C)C)N(C)C(CN2C)=O)=O)C(C3=NC4=C(C(N[C@H](C(N[C@H](C(C)C)C(N5[C@@]([H])(CCC5)C6=O)=O)=O)[C@@H](C)OC([C@H](C(C)C)N(C)C(CN6C)=O)=O)=O)C=CC(C)=C4OC3=C7C)=C(N)C7=O–Cancer; Infection–10 mM in DMSO–Antibiotic;Apoptosis;Bacterial—-Anti-infection;Apoptosis–Peptides