Description

Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)—-C27H38N6O12—-[1]Smith GK, et al. Expression, preparation, and high-throughput screening of caspase-8: discovery of redox-based and steroid diacid inhibition. Arch Biochem Biophys. 2002;399(2):195-205.–219138-21-3–638.62–98.73–O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(NC1=CC=C([N+]([O-])=O)C=C1)=O)=O)[C@H](CCC(O)=O)NC([C@@H](NC(C)=O)[C@@H](C)CC)=O–Others–10 mM in DMSO–Caspase—-Apoptosis–Peptides