Description

Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 is a cathepsin D substrate, that can be used for cathepsin D FRET assay[1].—–C104H146N24O23S—-[1]Eketjäll S, et al. AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics. J Alzheimers Dis. 2016;50(4):1109-23. –400716-78-1–2132.48—-O=S(O)(C1=CC=CC2=C1C=CC=C2NCCNC(C[C@H](NC([C@@H](NC(C)=O)CCC(O)=O)=O)C(N[C@@H](CCCCN)C(N3[C@@H](CCC3)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCCCNC(C4=CC=C(C=C4)/N=N/C5=CC=C(C=C5)N(C)C)=O)C(N[C@H](C(N)=O)CCC(O)=O)=O)=O)=O)=O)=O)CC6=CC=CC=C6)=O)CC7=CC=CC=C7)=O)=O)=O)=O)=O)=O)=O–Others–H2O–Cathepsin–Cathepsin D–Metabolic Enzyme/Protease–Peptides