Description

Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2 is the SH2 domain ligand. SH2 domains participate in protein tyrosine kinase (PTK)-mediated cellular signal[1].—–C36H56N7O13PS—-[1]Burke TR Jr, et al. Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors. Biochemistry. 1994 May 31;33(21):6490-4.–157382-69-9–857.91—-O=P(O)(O)OC(C=C1)=CC=C1C[C@H](NC([C@@H](NC(C)=O)CC(O)=O)=O)C(N[C@@H](C(C)C)C(N2[C@@H](CCC2)C(N[C@@H](CCSC)C(N[C@H](C(N)=O)CC(C)C)=O)=O)=O)=O–Metabolic Disease–10 mM in DMSO–Others—-Others–Peptides